Allogeneic bone marrow mesenchymal stem cell-derived exosomes alleviate human hypoxic AKI-on-a-Chip within a tight treatment window

Allogeneic bone marrow mesenchymal stem cell-derived exosomes alleviate human hypoxic AKI-on-a-Chip within a tight treatment window

Abstract Background Acute hypoxic proximal tubule (PT) injury and subsequent maladaptive repair present high mortality and increased risk of acute kidney injury (AKI) - chronic kidney disease (CKD) transition. Human bone marrow mesenchymal stem cell-derived exosomes (hBMMSC-Exos) as potential cell t...

Full description

Bibliographic Details
Main Authors: Sefa Burak Çam, Eda Çiftci, Nazlıhan Gürbüz, Bülent Altun, Petek Korkusuz
Format: Article
Language:English
Published: BMC 2024-04-01
Series:Stem Cell Research & Therapy
Subjects:
Ischemic AKI
Proximal tubule
Exosome
Kidney-on-a-chip
Hypoxia
Mesenchymal stem cells
Online Access:https://doi.org/10.1186/s13287-024-03674-8

Internet

https://doi.org/10.1186/s13287-024-03674-8

Similar Items