A method for determining potential parental contamination: linkage disequilibrium-based log-likelihood ratio analysis for IVF-PGT

A method for determining potential parental contamination: linkage disequilibrium-based log-likelihood ratio analysis for IVF-PGT

Abstract Background At present, embryologists are attempting to use conventional in vitro fertilization (cIVF) as an alternative to intracytoplasmic sperm injection (ICSI) for preimplantation genetic testing (PGT). However, the potential parental contamination origin of sperm cells and cumulus cells...

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Bibliographic Details
Main Authors: Le Bo, Fangfang Dong, Zhinan Wu, Anwen Zhou, Yulan Zhang, Lingyin Kong, Lei Zhan, Naru Lu, Lina Qi, Tingting Sun, Bo Liang, Caiping Mao
Format: Article
Language:English
Published: BMC 2024-10-01
Series:Reproductive Biology and Endocrinology
Subjects:
Conventional in vitro fertilization (cIVF)
Potential parental contamination
IVF-PGTA assay
Linkage disequilibrium (LD)
Log-likelihood ratio (LLR) analysis
Online Access:https://doi.org/10.1186/s12958-024-01300-z

Internet

https://doi.org/10.1186/s12958-024-01300-z

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