Translation of therapeutic strategies to modulate B cell reponses from non-human primate models to human kidney transplantation

Using novel drugs targeting lymphocyte costimulation, cytokines, antibody, complement, and plasma cells, we have developed strategies in a non-human primate model to modulate the B cell response to incompatible kidney transplants. After more than two decades of research supported by mechanistic stud...

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Bibliographic Details
Main Authors: Stuart Knechtle, Jean Kwun, Shengli Song, Annette Jackson, Kitza Williams, Scott Sanoff
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-04-01
Series:Frontiers in Transplantation
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/frtra.2023.1176796/full