<i>Curcuma phaeocaulis</i> Inhibits NLRP3 Inflammasome in Macrophages and Ameliorates Nanoparticle-Induced Airway Inflammation in Mice

<i>Curcuma phaeocaulis</i> Inhibits NLRP3 Inflammasome in Macrophages and Ameliorates Nanoparticle-Induced Airway Inflammation in Mice

The activation of NLRP3 results in the assembly of inflammasome that regulates caspase-1 activation and the subsequent secretion of bioactive interleukin (IL)-1β. Excessive activation of the NLRP3 inflammasome is mechanistically linked to diverse pathophysiological conditions, including airway infla...

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Bibliographic Details
Main Authors: Yeon-Ju Nam, Jiwon Choi, Jong Suk Lee, Changon Seo, Gyeongbeen Lee, Youngsu Lee, Jin Kyu Kim, Pansoo Kim, Jeong Ju Lim, Hyeon-Son Choi, Yongmun Choi
Format: Article
Language:English
Published: MDPI AG 2022-03-01
Series:Molecules
Subjects:
NLRP3
inflammasome
<i>Curcuma phaeocaulis</i> Valeton
interleukin-1β
curcumin
Online Access:https://www.mdpi.com/1420-3049/27/7/2101

Internet

https://www.mdpi.com/1420-3049/27/7/2101

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