The methyltransferase METTL3-mediated fatty acid metabolism revealed the mechanism of cinnamaldehyde on alleviating steatosis

Background: As a primarily N6-methyladenosine methyltransferase, methyltransferase 3 (METTL3) plays a crucial role in nonalcoholic fatty liver disease. However, its regulatory mechanism in steatosis remains unknown. Methods: Alpha mouse liver 12 (AML12) cells were induced by free fatty acids (FFA)....

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Bibliographic Details
Main Authors: Ruohui Xu, Xiaoli Xiao, Shengan Zhang, Jiashu Pan, Yingjue Tang, Wenjun Zhou, Guang Ji, Yanqi Dang
Format: Article
Language:English
Published: Elsevier 2022-09-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332222007569