The BAF chromatin remodeling complex licenses planarian stem cells access to ectodermal and mesodermal cell fates

The BAF chromatin remodeling complex licenses planarian stem cells access to ectodermal and mesodermal cell fates

Abstract Background The flatworm planarian, Schmidtea mediterranea, has a large population of adult stem cells (ASCs) that replace any cell type during tissue turnover or regeneration. How planarian ASCs (called neoblasts) manage self-renewal with the ability to produce daughter cells of different c...

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Bibliographic Details
Main Authors: Mallory Wiggans, Shu Jun Zhu, Alyssa M. Molinaro, Bret J. Pearson
Format: Article
Language:English
Published: BMC 2023-10-01
Series:BMC Biology
Subjects:
Adults stem cells
Stemness
Planarians
Chromatin remodeling
BAF complex
Brg1
Online Access:https://doi.org/10.1186/s12915-023-01730-y

Internet

https://doi.org/10.1186/s12915-023-01730-y

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