Fast and Accurate Surrogate Virus Neutralization Test Based on Antibody-Mediated Blocking of the Interaction of ACE2 and SARS-CoV-2 Spike Protein RBD

The humoral response to the SARS-CoV-2 S protein determines the development of protective immunity against this infection. The standard neutralizing antibodies detection method is a live virus neutralization test. It can be replaced with an ELISA-based surrogate virus neutralization test (sVNT), mea...

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Bibliographic Details
Main Authors: Denis E. Kolesov, Maria V. Sinegubova, Lutsia K. Dayanova, Inna V. Dolzhikova, Ivan I. Vorobiev, Nadezhda A. Orlova
Format: Article
Language:English
Published: MDPI AG 2022-02-01
Series:Diagnostics
Subjects:
Online Access:https://www.mdpi.com/2075-4418/12/2/393