TREM-1 Protects HIV-1-Infected Macrophages from Apoptosis through Maintenance of Mitochondrial Function

TREM-1 Protects HIV-1-Infected Macrophages from Apoptosis through Maintenance of Mitochondrial Function

ABSTRACT Macrophages are a reservoir for latent human immunodeficiency type 1 (HIV) infection and a barrier to HIV eradication. In contrast to CD4+ T cells, macrophages are resistant to the cytopathic effects of acute HIV infection. Emerging data suggest a role for TREM1 (triggering receptor express...

Full description

Bibliographic Details
Main Authors: Grant R. Campbell, Rachel K. To, Stephen A. Spector
Format: Article
Language:English
Published: American Society for Microbiology 2019-12-01
Series:mBio
Subjects:
BCL2 family
TREM-1
apoptosis
human immunodeficiency virus
macrophages
mitochondria
Online Access:https://journals.asm.org/doi/10.1128/mBio.02638-19

Internet

https://journals.asm.org/doi/10.1128/mBio.02638-19

Similar Items