Regulation of T cell afferent lymphatic migration by targeting LTβR-mediated non-classical NFκB signaling

Regulation of T cell afferent lymphatic migration by targeting LTβR-mediated non-classical NFκB signaling

Lymphotoxin beta receptor (LTβR) signalling regulates leukocyte migration through the lymphatic endothelial layers. Here, the authors show that treatment of an LTβR-derived decoy peptide can target the non-classical NFκB pathway to inhibit T cell and dendritic cell migration and ameliorate contact h...

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Bibliographic Details
Main Authors: Wenji Piao, Yanbao Xiong, Konrad Famulski, C. Colin Brinkman, Lushen Li, Nicholas Toney, Chelsea Wagner, Vikas Saxena, Thomas Simon, Jonathan S. Bromberg
Format: Article
Language:English
Published: Nature Portfolio 2018-08-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-018-05412-0

Internet

https://doi.org/10.1038/s41467-018-05412-0

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