In vitro elastic cartilage reconstruction using human auricular perichondrial chondroprogenitor cell–derived micro 3D spheroids

Morphologically stable scaffold-free elastic cartilage tissue is crucial for treating external ear abnormalities. However, establishing adequate mechanical strength is challenging, owing to the difficulty of achieving chondrogenic differentiation in vitro; thus, cartilage reconstruction is a complex...

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Bibliographic Details
Main Authors: Takayoshi Oba, Satoshi Okamoto, Yasuharu Ueno, Megumi Matsuo, Tomomi Tadokoro, Shinji Kobayashi, Kazunori Yasumura, Shintaro Kagimoto, Yutaka Inaba, Hideki Taniguchi
Format: Article
Language:English
Published: SAGE Publishing 2022-12-01
Series:Journal of Tissue Engineering
Online Access:https://doi.org/10.1177/20417314221143484