Sustained Expression of TDP-43 and FUS in Motor Neurons in Rodent's Lifetime

<p>TAR DNA-binding protein (TDP-43) and fused in sarcoma (FUS) are two highly conserved ribonucleoproteins. Pathogenic mutations of the <i>TDP-43</i> or the <i>FUS </i>gene are all linked to amyotrophic lateral sclerosis (ALS) that is characterized by progressive degene...

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Bibliographic Details
Main Author: Cao Huang, Pedro Yuxing Xia, Hongxia Zhou
Format: Article
Language:English
Published: Ivyspring International Publisher 2010-01-01
Series:International Journal of Biological Sciences
Online Access:http://www.biolsci.org/v06p0396.htm