Sustained Expression of TDP-43 and FUS in Motor Neurons in Rodent's Lifetime
<p>TAR DNA-binding protein (TDP-43) and fused in sarcoma (FUS) are two highly conserved ribonucleoproteins. Pathogenic mutations of the <i>TDP-43</i> or the <i>FUS </i>gene are all linked to amyotrophic lateral sclerosis (ALS) that is characterized by progressive degene...
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Format: | Article |
Language: | English |
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Ivyspring International Publisher
2010-01-01
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Series: | International Journal of Biological Sciences |
Online Access: | http://www.biolsci.org/v06p0396.htm |