A microfluidic device for simple and rapid evaluation of multidrug efflux pump inhibitors

A microfluidic device for simple and rapid evaluation of multidrug efflux pump inhibitors

Recently, multidrug resistant pathogens have disseminated widely owing essentially to their increased multidrug efflux pump activity. Presently, there is a scarcity of new antibacterial agents, and hence, inhibitors of multidrug efflux pumps belonging to the resistance-nodulation-cell division (RND)...

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Bibliographic Details
Main Authors: Ryota eIino, Kunihiko eNishino, Hiroyuki eNoji, Akihito eYamaguchi, Yoshimi eMatsumoto
Format: Article
Language:English
Published: Frontiers Media S.A. 2012-02-01
Series:Frontiers in Microbiology
Subjects:
Escherichia coli
Pseudomonas aeruginosa
Fluorescein-di-β-D-galactopyranoside
fluorescence microscopy
Microfluidic channel
Phe-Arg-β-naphthylamide
Online Access:http://journal.frontiersin.org/Journal/10.3389/fmicb.2012.00040/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fmicb.2012.00040/full

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