Profiling tyrosine kinase inhibitors as AD therapeutics in a mouse model of AD

Abstract Alzheimer’s disease (AD) is a neurodegenerative disease characterized by Aβ deposition, tauopathy, neuroinflammation, and impaired cognition. The recent identification of associations between protein kinases and AD pathology has spurred interest in tyrosine kinase inhibitors (TKIs) as poten...

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Bibliographic Details
Main Authors: Hyun-ju Lee, Jeong-Woo Hwang, Jin-Hee Park, Yoo Joo Jeong, Ji-Yeong Jang, Hyang-Sook Hoe
Format: Article
Language:English
Published: BMC 2023-08-01
Series:Molecular Brain
Subjects:
Online Access:https://doi.org/10.1186/s13041-023-01051-9