Targeting CD47 as a Novel Immunotherapy for Multiple Myeloma

Targeting CD47 as a Novel Immunotherapy for Multiple Myeloma

Multiple myeloma (MM) remains to be incurable despite recent therapeutic advances. CD47, an immune checkpoint known as the “don’t eat me” signal, is highly expressed on the surface of various cancers, allowing cancer cells to send inhibitory signals to macrophages and i...

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Bibliographic Details
Main Authors: Jennifer Sun, Barbara Muz, Kinan Alhallak, Matea Markovic, Shannon Gurley, Zhe Wang, Nicole Guenthner, Katherine Wasden, Mark Fiala, Justin King, Daniel Kohnen, Noha Nabil Salama, Ravi Vij, Abdel Kareem Azab
Format: Article
Language:English
Published: MDPI AG 2020-01-01
Series:Cancers
Subjects:
multiple myeloma
macrophages
checkpoint inhibitors
3d tissue culture model
Online Access:https://www.mdpi.com/2072-6694/12/2/305

Internet

https://www.mdpi.com/2072-6694/12/2/305

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