Rnd3 induces stress fibres in endothelial cells through RhoB

Summary Rnd proteins are atypical Rho family proteins that do not hydrolyse GTP and are instead regulated by expression levels and post-translational modifications. Rnd1 and Rnd3/RhoE induce loss of actin stress fibres and cell rounding in multiple cell types, whereas responses to Rnd2 are more vari...

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Bibliographic Details
Main Authors: Undine Gottesbühren, Ritu Garg, Philippe Riou, Brad McColl, Daniel Brayson, Anne J. Ridley
Format: Article
Language:English
Published: The Company of Biologists 2012-12-01
Series:Biology Open
Subjects:
Online Access:http://bio.biologists.org/content/2/2/210