Gene expression profiles among murine strains segregate with distinct differences in the progression of radiation-induced lung disease

Gene expression profiles among murine strains segregate with distinct differences in the progression of radiation-induced lung disease

Molecular mechanisms underlying development of acute pneumonitis and/or late fibrosis following thoracic irradiation remain poorly understood. Here, we hypothesize that heterogeneity in disease progression and phenotypic expression of radiation-induced lung disease (RILD) across murine strains prese...

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Bibliographic Details
Main Authors: Isabel L. Jackson, Fitsum Baye, Chirayu P. Goswami, Barry P. Katz, Andrew Zodda, Radmila Pavlovic, Ganga Gurung, Don Winans, Zeljko Vujaskovic
Format: Article
Language:English
Published: The Company of Biologists 2017-04-01
Series:Disease Models & Mechanisms
Subjects:
Radiation pneumonitis
Lung fibrosis
Gene expression profiling
Murine strain differences
Online Access:http://dmm.biologists.org/content/10/4/425

Internet

http://dmm.biologists.org/content/10/4/425

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