CRHR1 mediates the transcriptional expression of pituitary hormones and their receptors under hypoxia

CRHR1 mediates the transcriptional expression of pituitary hormones and their receptors under hypoxia

Hypothalamus-pituitary-adrenal (HPA) axis plays critical roles in stress responses under challenging conditions such as hypoxia, via regulating gene expression and integrating activities of hypothalamus-pituitary-targets cells. However, the transcriptional regulatory mechanisms and signaling pathway...

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Bibliographic Details
Main Authors: Tong Ying Wang, Fang Yuan Xia, Jing Wen Gong, Xiao Kang Xu, Min Chao Lv, Mahanand Chatoo, Bilal Haider Shamsi, Meng Chen Zhang, Qian Ru Liu, Tian Xing Liu, Dan Dan Zhang, Xin Jiang Lu, Yang Zhao, Ji Zeng Du, Xue Qun Chen
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-09-01
Series:Frontiers in Endocrinology
Subjects:
hypothalamus
hypoxia
transcription
pituitary
receptor
stress
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2022.893238/full

Internet

https://www.frontiersin.org/articles/10.3389/fendo.2022.893238/full

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