The Peculiar Estrogenicity of Diethyl Phthalate: Modulation of Estrogen Receptor α Activities in the Proliferation of Breast Cancer Cells

The Peculiar Estrogenicity of Diethyl Phthalate: Modulation of Estrogen Receptor α Activities in the Proliferation of Breast Cancer Cells

Phthalates comprise a group of synthetic chemicals present in the environment because of their wide use as plasticizers and as additives in products for personal care. Among others, diethyl phthalate (DEP) is largely used in products for infants, children, and adults, in which its exposure has been...

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Bibliographic Details
Main Authors: Marco Fiocchetti, Giovanna Bastari, Manuela Cipolletti, Stefano Leone, Filippo Acconcia, Maria Marino
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:Toxics
Subjects:
diethyl phthalate
endocrine disruptors
estrogen receptor α
signal transduction pathways
breast cancer cell proliferation
Online Access:https://www.mdpi.com/2305-6304/9/10/237

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https://www.mdpi.com/2305-6304/9/10/237

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