Analgesic-like activity of perillyl acetate: In vivo and in silico studies

Analgesic-like activity of perillyl acetate: In vivo and in silico studies

Objective: To evaluate the antinociceptive activity of perillyl acetate in mice and in silico simulations. Methods: The vehicle, perillyl acetate (100, 150 and/or 200 mg/ kg, i.p.), diazepam (2 mg/kg, i.p.) or morphine (6 mg/kg, i.p.) was administered to mice, respectively. Rotarod test, acetic acid...

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Bibliographic Details
Main Authors: Renan Braga, Humberto Andrade, Ryldene Cruz, Mayara Maia, Carolina Lima, Anderson Santos, André Miranda, Allana Duarte, Marcus Scotti, Reinaldo Almeida, Damião Sousa
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2022-01-01
Series:Asian Pacific Journal of Tropical Biomedicine
Subjects:
analgesic; biological products; opioid; essential oil; pain; monoterpene; perillyl acetate
Online Access:http://www.apjtb.org/article.asp?issn=2221-1691;year=2022;volume=12;issue=4;spage=156;epage=163;aulast=Braga

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http://www.apjtb.org/article.asp?issn=2221-1691;year=2022;volume=12;issue=4;spage=156;epage=163;aulast=Braga

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