Analgesic-like activity of perillyl acetate: In vivo and in silico studies
Objective: To evaluate the antinociceptive activity of perillyl acetate in mice and in silico simulations. Methods: The vehicle, perillyl acetate (100, 150 and/or 200 mg/ kg, i.p.), diazepam (2 mg/kg, i.p.) or morphine (6 mg/kg, i.p.) was administered to mice, respectively. Rotarod test, acetic acid...
Main Authors: | Renan Braga, Humberto Andrade, Ryldene Cruz, Mayara Maia, Carolina Lima, Anderson Santos, André Miranda, Allana Duarte, Marcus Scotti, Reinaldo Almeida, Damião Sousa |
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Format: | Article |
Language: | English |
Published: |
Wolters Kluwer Medknow Publications
2022-01-01
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Series: | Asian Pacific Journal of Tropical Biomedicine |
Subjects: | |
Online Access: | http://www.apjtb.org/article.asp?issn=2221-1691;year=2022;volume=12;issue=4;spage=156;epage=163;aulast=Braga |
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