Tubercidin inhibits PRRSV replication via RIG-I/NF-κB pathways and interrupting viral nsp2 synthesis

Tubercidin inhibits PRRSV replication via RIG-I/NF-κB pathways and interrupting viral nsp2 synthesis

ABSTRACTPorcine reproductive and respiratory syndrome virus (PRRSV) is an RNA virus with constantly emerging recombinant and mutant strains. Because of the high genetic diversity of PRRSV, current vaccines only provide partial protection against the infection of heterologous strains, which makes it...

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Bibliographic Details
Main Authors: Yuqian Xu, Zhenbang Zhu, Meng Zhang, Lulu Chen, Kegong Tian, Xiangdong Li
Format: Article
Language:English
Published: American Society for Microbiology 2024-03-01
Series:Microbiology Spectrum
Subjects:
PRRSV
tubercidin
antiviral activity
nsp2
cytokines
Online Access:https://journals.asm.org/doi/10.1128/spectrum.03479-23

Internet

https://journals.asm.org/doi/10.1128/spectrum.03479-23

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