Identification of Novel Imatinib-Resistant Genes in Gastrointestinal Stromal Tumors

Identification of Novel Imatinib-Resistant Genes in Gastrointestinal Stromal Tumors

Gastrointestinal stromal tumors (GISTs) are common ICC precursor sarcomas, which are considered to be a potential malignant mesenchymal tumor driven by specific KIT or PDGFRA signals in the gastrointestinal tract. The standard treatment for GIST without metastasis is surgical resection. GIST with me...

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Bibliographic Details
Main Authors: Lei Cao, Kunming Zheng, Yanhong Liu, Peng Song, Chuntao Wang, Hongzhi Wang, Nan Wang, Shiwu Zhang, Yongjie Zhao
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-05-01
Series:Frontiers in Genetics
Subjects:
GIST
gastrointestinal stromal tumor
imatinib
DEG (differentially expressed gene) analysis
resistance
gene chip
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2022.878145/full

Internet

https://www.frontiersin.org/articles/10.3389/fgene.2022.878145/full

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