The Association of Increase of Human T-Cell Leukemia Virus Type-1 (HTLV-1) Proviral Load (PVL) With Infection in HTLV-1-Positive Patients With Rheumatoid Arthritis: A Longitudinal Analysis of Changes in HTLV-1 PVLs in a Single Center Cohort Study

The Association of Increase of Human T-Cell Leukemia Virus Type-1 (HTLV-1) Proviral Load (PVL) With Infection in HTLV-1-Positive Patients With Rheumatoid Arthritis: A Longitudinal Analysis of Changes in HTLV-1 PVLs in a Single Center Cohort Study

ObjectiveWe evaluated changes of HTLV-1 proviral loads (PVLs) during treatment for rheumatoid arthritis (RA) and investigated whether these changes affect the clinical course in HTLV-1-positive RA patients.MethodsA total of 41 HTLV-1-positive RA patients were analyzed. Their clinical picture includi...

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Bibliographic Details
Main Authors: Naoki Iwamoto, Takeshi Araki, Ayaka Umetsu, Ayuko Takatani, Toshiyuki Aramaki, Kunihiro Ichinose, Kaoru Terada, Naoyuki Hirakata, Yukitaka Ueki, Atsushi Kawakami, Katsumi Eguchi
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-05-01
Series:Frontiers in Immunology
Subjects:
rheumatoid arthritis
human T-cell leukemia virus type 1
proviral load
infection
molecular-targeted therapy
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.887783/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2022.887783/full

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