The clinical and molecular significance associated with STING signaling in breast cancer

Abstract STING signaling in cancer is a crucial component of response to immunotherapy and other anti-cancer treatments. Currently, there is no robust method of measuring STING activation in cancer. Here, we describe an immunohistochemistry-based assay with digital pathology assessment of STING in t...

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Bibliographic Details
Main Authors: Eileen E. Parkes, Matthew P. Humphries, Elaine Gilmore, Fatima A. Sidi, Victoria Bingham, Su M. Phyu, Stephanie Craig, Catherine Graham, Joseph Miller, Daryl Griffin, Manuel Salto-Tellez, Stephen F. Madden, Richard D. Kennedy, Samuel F. Bakhoum, Stephen McQuaid, Niamh E. Buckley
Format: Article
Language:English
Published: Nature Portfolio 2021-06-01
Series:npj Breast Cancer
Online Access:https://doi.org/10.1038/s41523-021-00283-z