The clinical and molecular significance associated with STING signaling in breast cancer
Abstract STING signaling in cancer is a crucial component of response to immunotherapy and other anti-cancer treatments. Currently, there is no robust method of measuring STING activation in cancer. Here, we describe an immunohistochemistry-based assay with digital pathology assessment of STING in t...
| Main Authors: | Eileen E. Parkes, Matthew P. Humphries, Elaine Gilmore, Fatima A. Sidi, Victoria Bingham, Su M. Phyu, Stephanie Craig, Catherine Graham, Joseph Miller, Daryl Griffin, Manuel Salto-Tellez, Stephen F. Madden, Richard D. Kennedy, Samuel F. Bakhoum, Stephen McQuaid, Niamh E. Buckley |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2021-06-01
|
| Series: | npj Breast Cancer |
| Online Access: | https://doi.org/10.1038/s41523-021-00283-z |
Similar Items
-
Exploring the immune microenvironment in small bowel adenocarcinoma using digital image analysis.
by: Fatima Abdullahi Sidi, et al.
Published: (2023-01-01) -
Activation of STING-dependent innate immune signaling by S-phase-specific DNA damage in breast cancer
by: Parkes, EE, et al.
Published: (2016) -
Pin1 plays a key role in the response to treatment and clinical outcome in triple negative breast cancer
by: Catherine Knowlson, et al.
Published: (2020-03-01) -
NUP98 – a novel predictor of response to anthracycline-based chemotherapy in triple negative breast cancer
by: Paul B. Mullan, et al.
Published: (2019-04-01) -
Topographic analysis of pancreatic cancer by TMA and digital spatial profiling reveals biological complexity with potential therapeutic implications
by: Victoria Bingham, et al.
Published: (2024-05-01)