RNA binding protein PCBP1 regulates hESC pluripotency through modulating mRNA export

RNA binding protein PCBP1 regulates hESC pluripotency through modulating mRNA export

Objective To investigate the biological function of RNA binding protein polycytosine-binding protein 1 (PCBP1) in the maintenance of pluripotency of human embryonic stem cells (hESC) and to explore the new mechanism of regulating hESC pluripotency. Methods PCBP1 knockdown technology was used to dete...

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Bibliographic Details
Main Author: XU Jia-yue, YANG Jia-bin, CHEN Zhong-yang, YU Jia, MA Yan-ni
Format: Article
Language:zho
Published: Institute of Basic Medical Sciences and Peking Union Medical College Hospital, Chinese Academy of Medical Sciences / Peking Union Medical College. 2022-02-01
Series:Jichu yixue yu linchuang
Subjects:
human embryonic stem cell|polycytosine binding protein 1|pluripotency and self-renewal|nuclear and cytoplasm extraction
Online Access:http://journal11.magtechjournal.com/Jwk_jcyxylc/fileup/1001-6325/PDF/1001-6325-2022-42-2-228.pdf

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http://journal11.magtechjournal.com/Jwk_jcyxylc/fileup/1001-6325/PDF/1001-6325-2022-42-2-228.pdf

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