Modulation of microglial metabolism facilitates regeneration in demyelination

Summary: Microglia exhibit diverse phenotypes in various central nervous system disorders and metabolic pathways exert crucial effects on microglial activation and effector functions. Here, we discovered two novel distinct microglial clusters, functionally associated with enhanced phagocytosis (PEMs...

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Bibliographic Details
Main Authors: Chuan Qin, Sheng Yang, Man Chen, Ming-Hao Dong, Luo-Qi Zhou, Yun-Hui Chu, Zhu-Xia Shen, Dale B. Bosco, Long-Jun Wu, Dai-Shi Tian, Wei Wang
Format: Article
Language:English
Published: Elsevier 2023-05-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S258900422300665X