Improvement in low-homology template-based modeling by employing a model evaluation method with focus on topology.

Many template-based modeling (TBM) methods have been developed over the recent years that allow for protein structure prediction and for the study of structure-function relationships for proteins. One major problem all TBM algorithms face, however, is their unsatisfactory performance when proteins u...

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Bibliographic Details
Main Authors: Wentao Dai, Tingrui Song, Xuan Wang, Xiaoyang Jin, Lizong Deng, Aiping Wu, Taijiao Jiang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0089935&type=printable