Caspase-1 variant influencing CSF tau and FDG PET levels in non-demented elders from the ADNI cohort

Caspase-1 variant influencing CSF tau and FDG PET levels in non-demented elders from the ADNI cohort

Abstract Background Genetic variations in the inflammatory Caspase-1 gene have been shown associated with cognitive function in elderly individuals and in predisposition to Alzheimer’s disease (AD), but its detailed mechanism before the typical AD onset was still unclear. Our current study evaluated...

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Bibliographic Details
Main Authors: Yi Liu, Meng-Shan Tan, Zuo-Teng Wang, Wei Xu, Lan Tan
Format: Article
Language:English
Published: BMC 2022-02-01
Series:BMC Neurology
Subjects:
Caspase-1
Variant
CSF
Tau pathology
FDG PET
Neurodegeneration
Online Access:https://doi.org/10.1186/s12883-022-02582-9

Internet

https://doi.org/10.1186/s12883-022-02582-9

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