Chemotherapy-Induced Changes in the Lung Microenvironment: The Role of MMP-2 in Facilitating Intravascular Arrest of Breast Cancer Cells
Previously, we showed that mice treated with cyclophosphamide (CTX) 4 days before intravenous injection of breast cancer cells had more cancer cells in the lung at 3 h after cancer injection than control counterparts without CTX. At 4 days after its injection, CTX is already excreted from the mice,...
Main Authors: | Justin D. Middleton, Subhakeertana Sivakumar, Tsonwin Hai |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2021-09-01
|
Series: | International Journal of Molecular Sciences |
Subjects: | |
Online Access: | https://www.mdpi.com/1422-0067/22/19/10280 |
Similar Items
-
Matrix Metalloproteases in Pancreatic Ductal Adenocarcinoma: Key Drivers of Disease Progression?
by: Etienne J. Slapak, et al.
Published: (2020-04-01) -
Activity Dependent CAM cleavage and Neurotransmission
by: Katherine eConant, et al.
Published: (2015-08-01) -
Stress-Inducible Gene <i>Atf3</i> Dictates a Dichotomous Macrophage Activity in Chemotherapy-Enhanced Lung Colonization
by: Justin D. Middleton, et al.
Published: (2021-07-01) -
Clinical Significance of MMP7 Levels in Colorectal Cancer Patients Receiving FOLFOX4 Chemotherapy Treatment
by: Zhou Y, et al.
Published: (2023-06-01) -
Regulation of MT1-MMP and MMP-2 by the Serpin PEDF: a Promising New Target for Metastatic Cancer
by: Marice B. Alcantara, et al.
Published: (2012-03-01)