Fucoidan alleviates the hepatorenal syndrome through inhibition organic solute transporter α/β to reduce bile acids reabsorption

The high levels of bile acids are a critical factor in hepatorenal syndrome. Organic solute transporter α/β (Ostα/β) participate in bile acids reabsorption in the kidney. Fucoidan has the great potential in protecting against liver and kidney injury. However, whether Ostα/β increase bile acids reabs...

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Bibliographic Details
Main Authors: Xiaojuan Zhao, Ting Yang, Jiayan Zhou, Yanli Chen, Qian Shen, Jiankang Zhang, Qianqian Qiu
Format: Article
Language:English
Published: Elsevier 2023-01-01
Series:Current Research in Pharmacology and Drug Discovery
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S259025712300007X