An adhesion signaling axis involving Dystroglycan, β1-Integrin, and Cas adaptor proteins regulates the establishment of the cortical glial scaffold.

The mature mammalian cortex is composed of 6 architecturally and functionally distinct layers. Two key steps in the assembly of this layered structure are the initial establishment of the glial scaffold and the subsequent migration of postmitotic neurons to their final position. These processes invo...

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Bibliographic Details
Main Authors: Wenny Wong, Jason A Estep, Alyssa M Treptow, Niloofar Rajabli, Jennifer N Jahncke, Teresa Ubina, Kevin M Wright, Martin M Riccomagno
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2023-08-01
Series:PLoS Biology
Online Access:https://journals.plos.org/plosbiology/article/file?id=10.1371/journal.pbio.3002212&type=printable