Chiral phosphoric acid-catalyzed enantioselective phosphinylation of 3,4-dihydroisoquinolines with diarylphosphine oxides
Catalytic enantioselective phosphinylation of imines with diarylphosphine oxides is a powerful approach to access chiral α-amino diarylphosphine oxides. Here, the authors report the asymmetric phosphinylation of 3,4-dihydroisoquinolines at the C1 position using diarylphosphine oxides, catalyzed by c...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2023-02-01
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| Series: | Communications Chemistry |
| Online Access: | https://doi.org/10.1038/s42004-023-00826-4 |