Regulatory patterns analysis of transcription factor binding site clustered regions and identification of key genes in endometrial cancer

Regulatory patterns analysis of transcription factor binding site clustered regions and identification of key genes in endometrial cancer

Endometrial cancer (EC) is one of the three fatal tumors of the female reproductive system. Epigenetic alterations have been reported to be important in tumorigenesis, especially the chromatin accessibility changes and transcription factor binding differences. However, the regulatory mechanism under...

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Bibliographic Details
Main Authors: Xiaohan Tang, Junting Wang, Huan Tao, Lin Yuan, Guifang Du, Yang Ding, Kang Xu, Xuemei Bai, Yaru Li, Yu Sun, Xin Huang, Xiushuang Zheng, Qianqian Li, Bowen Gong, Yang Zheng, Jingxuan Xu, Xiang Xu, Zhe Wang, Xiaochen Bo, Meisong Lu, Hao Li, Hebing Chen
Format: Article
Language:English
Published: Elsevier 2022-01-01
Series:Computational and Structural Biotechnology Journal
Subjects:
Endometrial cancer
ATAC-seq
TFCR
Transcriptional regulation
Diagnostic biomarkers
Online Access:http://www.sciencedirect.com/science/article/pii/S2001037022000216

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http://www.sciencedirect.com/science/article/pii/S2001037022000216

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