Targeting transitioning lung monocytes/macrophages as treatment strategies in lung disease related to environmental exposures

Targeting transitioning lung monocytes/macrophages as treatment strategies in lung disease related to environmental exposures

Abstract Background Environmental/occupational exposures cause significant lung diseases. Agricultural organic dust extracts (ODE) and bacterial component lipopolysaccharide (LPS) induce recruited, transitioning murine lung monocytes/macrophages, yet their cellular role remains unclear. Methods CCR2...

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Bibliographic Details
Main Authors: Aaron D. Schwab, Todd A. Wyatt, Grace Moravec, Geoffrey M. Thiele, Amy J. Nelson, Angela Gleason, Oliver Schanze, Michael J. Duryee, Debra J. Romberger, Ted R. Mikuls, Jill A. Poole
Format: Article
Language:English
Published: BMC 2024-04-01
Series:Respiratory Research
Subjects:
Endotoxin
Organic dust
Immunology
Inflammation
Lung disease
Monocytes
Online Access:https://doi.org/10.1186/s12931-024-02804-3

Internet

https://doi.org/10.1186/s12931-024-02804-3

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