Investigating the role of Caspase-1 in a mouse model of Juvenile X-linked Retinoschisis

Investigating the role of Caspase-1 in a mouse model of Juvenile X-linked Retinoschisis

PurposePrevious studies have reported Caspase-1 (Casp1) is upregulated in mouse models of Juvenile X-linked Retinoschisis (XLRS), however no functional role for Casp1 in disease progression has been identified. We performed electroretinogram (ERG) and standardized optical coherence tomography (OCT)...

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Bibliographic Details
Main Authors: Ella J. Gehrke, Araniko Pandey, Jacob Thompson, Sajag Bhattarai, Prajwal Gurung, Ying Hsu, Arlene V. Drack
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-06-01
Series:Frontiers in Medicine
Subjects:
X-linked Retinoschisis
retinoschisin
disease mechanisms
Caspase-1
immunology
apoptosis
Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2024.1347599/full

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https://www.frontiersin.org/articles/10.3389/fmed.2024.1347599/full

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