Review of the direct and indirect effects of hyperglycemia on the HPA axis in T2DM and the co-occurrence of depression

Type 2 diabetes mellitus (T2DM) is characterized by persistent hyperglycemia which is further associated with hyperactivity of the hypothalamic-pituitary-adrenal (HPA) axis. Several studies have shown that HPA axis hyperactivity is heightened in the chronic hyperglycemic state with severe hyperglyce...

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Bibliographic Details
Main Authors: Andile Khathi, Palesa Mosili, Bongeka Cassandra Mkhize, Ntethelelo Hopewell Sibiya, Phikelelani Sethu Ngubane
Format: Article
Language:English
Published: BMJ Publishing Group 2024-02-01
Series:BMJ Open Diabetes Research & Care
Online Access:https://drc.bmj.com/content/12/1/e003218.full