Genetic circuit characterization by inferring RNA polymerase movement and ribosome usage

Debugging a genetic circuit is frustrated by the inability to characterize parts in the context of the circuit. Here the authors use RNA-seq and ribosome profiling to take ‘snapshots’ of a large circuit in different states.

Bibliografiset tiedot
Päätekijät: Amin Espah Borujeni, Jing Zhang, Hamid Doosthosseini, Alec A. K. Nielsen, Christopher A. Voigt
Aineistotyyppi: Artikkeli
Kieli:English
Julkaistu: Nature Portfolio 2020-10-01
Sarja:Nature Communications
Linkit:https://doi.org/10.1038/s41467-020-18630-2