Genetic circuit characterization by inferring RNA polymerase movement and ribosome usage

Debugging a genetic circuit is frustrated by the inability to characterize parts in the context of the circuit. Here the authors use RNA-seq and ribosome profiling to take ‘snapshots’ of a large circuit in different states.

ग्रंथसूची विवरण
मुख्य लेखकों: Amin Espah Borujeni, Jing Zhang, Hamid Doosthosseini, Alec A. K. Nielsen, Christopher A. Voigt
स्वरूप: लेख
भाषा:English
प्रकाशित: Nature Portfolio 2020-10-01
श्रृंखला:Nature Communications
ऑनलाइन पहुंच:https://doi.org/10.1038/s41467-020-18630-2