MnTnHex-2-PyP<sup>5+</sup> Displays Anticancer Properties and Enhances Cisplatin Effects in Non-Small Cell Lung Cancer Cells

MnTnHex-2-PyP<sup>5+</sup> Displays Anticancer Properties and Enhances Cisplatin Effects in Non-Small Cell Lung Cancer Cells

The manganese(III) porphyrin MnTnHex-2-PyP<sup>5+</sup> (MnTnHex) is a potent superoxide dismutase mimic and modulator of redox-based transcriptional activity that has been studied in the context of different human disease models, including cancer. Nevertheless, for lung cancer, hardly a...

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Bibliographic Details
Main Authors: Rita B. Soares, Rita Manguinhas, João G. Costa, Nuno Saraiva, Nuno Gil, Rafael Rosell, Sérgio P. Camões, Ines Batinic-Haberle, Ivan Spasojevic, Matilde Castro, Joana P. Miranda, Filipa Amaro, Joana Pinto, Ana S. Fernandes, Paula Guedes de Pinho, Nuno G. Oliveira
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:Antioxidants
Subjects:
non-small cell lung cancer
SOD mimic
MnTnHex-2-PyP<sup>5+</sup>
metabolomics
cytotoxicity
cisplatin
Online Access:https://www.mdpi.com/2076-3921/11/11/2198

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https://www.mdpi.com/2076-3921/11/11/2198

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