T cells, more than antibodies, may prevent symptoms developing from respiratory syncytial virus infections in older adults

T cells, more than antibodies, may prevent symptoms developing from respiratory syncytial virus infections in older adults

IntroductionThe immune mechanisms supporting partial protection from reinfection and disease by the respiratory syncytial virus (RSV) have not been fully characterized. In older adults, symptoms are typically mild but can be serious in patients with comorbidities when the infection extends to the lo...

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Bibliographic Details
Main Authors: Bruno Salaun, Jonathan De Smedt, Charlotte Vernhes, Annick Moureau, Deniz Öner, Arangassery Rosemary Bastian, Michel Janssens, Sunita Balla-Jhagjhoorsingh, Jeroen Aerssens, Christophe Lambert, Samuel Coenen, Christopher C. Butler, Simon B. Drysdale, Joanne G. Wildenbeest, Andrew J. Pollard, Peter J. M. Openshaw, Louis Bont
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-10-01
Series:Frontiers in Immunology
Subjects:
respiratory syncytial virus
cell-mediated immunity
correlate of protection
interferon-gamma
T-cell memory
CD4+ T cell
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1260146/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2023.1260146/full

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