The epithelial sodium channel in inflammation and blood pressure modulation

The epithelial sodium channel in inflammation and blood pressure modulation

A major regulator of blood pressure and volume homeostasis in the kidney is the epithelial sodium channel (ENaC). ENaC is composed of alpha(α)/beta(β)/gamma(γ) or delta(δ)/beta(β)/gamma(γ) subunits. The δ subunit is functional in the guinea pig, but not in routinely used experimental rodent models i...

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Bibliographic Details
Main Authors: Taseer Ahmad, Lale A. Ertuglu, Sepiso K. Masenga, Thomas R. Kleyman, Annet Kirabo
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-04-01
Series:Frontiers in Cardiovascular Medicine
Subjects:
epithelial sodium channel (ENaC)
δ-ENaC
antigen presenting cells
inflammation
endothelium dysfunction
blood pressure
Online Access:https://www.frontiersin.org/articles/10.3389/fcvm.2023.1130148/full

Internet

https://www.frontiersin.org/articles/10.3389/fcvm.2023.1130148/full

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