Genome-Wide Association Study of Beta-Blocker Survival Benefit in Black and White Patients with Heart Failure with Reduced Ejection Fraction

Genome-Wide Association Study of Beta-Blocker Survival Benefit in Black and White Patients with Heart Failure with Reduced Ejection Fraction

In patients with heart failure with reduced ejection fraction (HFrEF), individual responses to beta-blockers vary. Candidate gene pharmacogenetic studies yielded significant but inconsistent results, and they may have missed important associations. Our objective was to use an unbiased genome-wide as...

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Bibliographic Details
Main Authors: Jasmine A. Luzum, Alessandra M. Campos-Staffico, Jia Li, Ruicong She, Hongsheng Gui, Edward L. Peterson, Bin Liu, Hani N. Sabbah, Mark P. Donahue, William E. Kraus, L. Keoki Williams, David E. Lanfear
Format: Article
Language:English
Published: MDPI AG 2023-10-01
Series:Genes
Subjects:
beta-blocker
heart failure with reduced ejection fraction
survival
genome-wide association study
Online Access:https://www.mdpi.com/2073-4425/14/11/2019

Internet

https://www.mdpi.com/2073-4425/14/11/2019

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