A genome-wide association, polygenic risk score and sex study on opioid use disorder treatment outcomes

Abstract Opioid use disorder continues to be a health concern with a high rate of opioid related deaths occurring worldwide. Medication Assisted Treatments (MAT) have been shown to reduce opioid withdrawal, cravings and opioid use, however variability exists in individual’s treatment outcomes. Sex-s...

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Bibliographic Details
Main Authors: Alannah McEvoy, Caroul Chawar, Amel Lamri, Jacqueline Hudson, Luciano Minuzzi, David C. Marsh, Lehana Thabane, Andrew D. Paterson, Zainab Samaan
Format: Article
Language:English
Published: Nature Portfolio 2023-12-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-49605-0