Association between Hypothyroidism Onset and Alzheimer Disease Onset in Adults with Down Syndrome

Association between Hypothyroidism Onset and Alzheimer Disease Onset in Adults with Down Syndrome

Adults with Down syndrome (DS) have an exceptionally high frequency of Alzheimer disease (AD) with a wide variability in onset, from 40 to 70 years of age. Equally prevalent in DS is hypothyroidism. In this study, we sought to quantify the relationship between the two. A total of 232 adults with DS...

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Bibliographic Details
Main Authors: Florence Lai, Nathaniel D. Mercaldo, Cassandra M. Wang, Micaela S. Hersch, Giovi G. Hersch, Herminia Diana Rosas
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:Brain Sciences
Subjects:
Down syndrome
early-onset Alzheimer disease
late-onset Alzheimer disease
hypothyroidism
thyroid autoantibodies
TSH
Online Access:https://www.mdpi.com/2076-3425/11/9/1223

Internet

https://www.mdpi.com/2076-3425/11/9/1223

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