A Fatty Diet Induces a Jejunal Ketogenesis Which Inhibits Local SGLT1-Based Glucose Transport via an Acetylation Mechanism—Results from a Randomized Cross-Over Study between Iso-Caloric High-Fat versus High-Carbohydrate Diets in Healthy Volunteers

A Fatty Diet Induces a Jejunal Ketogenesis Which Inhibits Local SGLT1-Based Glucose Transport via an Acetylation Mechanism—Results from a Randomized Cross-Over Study between Iso-Caloric High-Fat versus High-Carbohydrate Diets in Healthy Volunteers

Background and aims: Insights into the nature of gut adaptation after different diets enhance the understanding of how food modifications can be used to treat type 2 diabetes and obesity. The aim was to understand how diets, enriched in fat or carbohydrates, affect glucose absorption in the human he...

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Bibliographic Details
Main Authors: Erik Elebring, Ville Wallenius, Anna Casselbrant, Neil G. Docherty, Carel W. le Roux, Hanns-Ulrich Marschall, Lars Fändriks
Format: Article
Language:English
Published: MDPI AG 2022-05-01
Series:Nutrients
Subjects:
jejunum
mucosa
monosaccharides
histone acetylation
Online Access:https://www.mdpi.com/2072-6643/14/9/1961

Internet

https://www.mdpi.com/2072-6643/14/9/1961

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