Mitochondrial complex II and reactive oxygen species in disease and therapy

Increasing evidence points to the respiratory Complex II (CII) as a source and modulator of reactive oxygen species (ROS). Both functional loss of CII as well as its pharmacological inhibition can lead to ROS generation in cells, with a relevant impact on the development of pathophysiological condit...

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Bibliographic Details
Main Authors: Katerina Hadrava Vanova, Michal Kraus, Jiri Neuzil, Jakub Rohlena
Format: Article
Language:English
Published: Taylor & Francis Group 2020-01-01
Series:Redox Report
Subjects:
Online Access:http://dx.doi.org/10.1080/13510002.2020.1752002