N-alkylimidazole derivatives as potential inhibitors of quorum sensing in Pseudomonas aeruginosa

N-alkylimidazole derivatives as potential inhibitors of quorum sensing in Pseudomonas aeruginosa

Antimicrobial resistance is a threat to global public health. Microbial resistance is mediated by biofilm formation and virulence behavior during infection. Quorum sensing (QS), a cell-to-cell communication is frequently used by microbes to evade host immune systems. Inhibiting QS channels is a pote...

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Bibliographic Details
Main Authors: Caleb Nketia Mensah, Gilbert Boadu Ampomah, Jehoshaphat Oppong Mensah, Edward Ntim Gasu, Caleb Impraim Aboagye, Edmund Ekuadzi, Nathaniel Owusu Boadi, Lawrence Sheringham Borquaye
Format: Article
Language:English
Published: Elsevier 2022-12-01
Series:Heliyon
Subjects:
Pyocyanin
LasR
Virulence factor
Biofilm inhibition
Imidazole derivatives
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844022038695

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http://www.sciencedirect.com/science/article/pii/S2405844022038695

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