Interleukin-11/IL-11 Receptor Promotes Glioblastoma Cell Proliferation, Epithelial–Mesenchymal Transition, and Invasion

Interleukin-11/IL-11 Receptor Promotes Glioblastoma Cell Proliferation, Epithelial–Mesenchymal Transition, and Invasion

Glioblastoma is highly proliferative and invasive. However, the regulatory cytokine networks that promote glioblastoma cell proliferation and invasion into other areas of the brain are not fully defined. In the present study, we define a critical role for the IL-11/IL-11Rα signalling axis in gliobla...

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Bibliographic Details
Main Authors: Sarah F. Stuart, Peter Curpen, Adele J. Gomes, Michelle C. Lan, Shuai Nie, Nicholas A. Williamson, George Kannourakis, Andrew P. Morokoff, Adrian A. Achuthan, Rodney B. Luwor
Format: Article
Language:English
Published: MDPI AG 2024-01-01
Series:Brain Sciences
Subjects:
interleukin 11
glioblastoma
EMT
invasion
Online Access:https://www.mdpi.com/2076-3425/14/1/89

Internet

https://www.mdpi.com/2076-3425/14/1/89

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