YAP/TAZ Promote Fibrotic Activity in Human Trabecular Meshwork Cells by Sensing Cytoskeleton Structure Alternation

YAP/TAZ Promote Fibrotic Activity in Human Trabecular Meshwork Cells by Sensing Cytoskeleton Structure Alternation

Trabecular meshwork (TM) is the main channel of aqueous humor (AH) outflow and the crucial tissue responsible for intraocular pressure (IOP) regulation. The aberrant fibrotic activity of human TM (HTM) cells is thought to be partially responsible for the increased resistance to AH outflow and elevat...

Full description

Bibliographic Details
Main Authors: Shan Huang, Zhicheng Liu, Xiuqing Qian, Lin Li, Haixia Zhang, Shanshan Li
Format: Article
Language:English
Published: MDPI AG 2022-06-01
Series:Chemosensors
Subjects:
trabecular meshwork
extracellular matrix
fibrotic activity
cytoskeleton
Online Access:https://www.mdpi.com/2227-9040/10/7/235

Internet

https://www.mdpi.com/2227-9040/10/7/235

Similar Items